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What is Adderall ?

an image of the amphetamine skeletal formula
a 3d image of the dextroamphetamine compound found in Adderall
Combination of
amphetamine aspartate monohydrate 25% – stimulant
(12.5% levo; 12.5% dextro)
amphetamine sulfate 25% – stimulant
(12.5% levo; 12.5% dextro)
dextroamphetamine saccharate 25% – stimulant
(0% levo; 25% dextro)
dextroamphetamine sulfate 25% – stimulant
(0% levo; 25% dextro)
Clinical data
Trade names Adderall, Adderall XR, Mydayis
AHFS/ Monograph
MedlinePlus a601234
License data
  • US: C (Risk not ruled out)
Physical: none[1]
Psychological: moderate[2]
Routes of
ATC code
Legal status
Legal status
CAS Number
PubChem CID

Adderall,[note 1] Adderall XR, and Mydayis are combination drugs containing four salts of the two enantiomers of amphetamine, a central nervous system (CNS) stimulant of the phenethylamine class. Adderall is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance enhancerand cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. By salt content, the active ingredients of Adderall, Adderall XR, and Mydayis are 25% levoamphetamine salts (the levorotatory or ‘left-handed’ enantiomer) and 75% dextroamphetamine salts (the dextrorotatory or ‘right-handed’ enantiomer).[note 2][sources 1]

Adderall is generally well-tolerated and effective in treating the symptoms of ADHD and narcolepsy. At therapeutic doses, Adderall causes emotional and cognitive effects such as euphoria, change in desire for sex, increased wakefulness, and improved cognitive control. At these doses, it induces physical effects such as a faster reaction time, fatigue resistance, and increased muscle strength. In contrast, much larger doses of Adderall can impair cognitive control, cause rapid muscle breakdown, or induce a psychosis (e.g., delusions and paranoia). The side effects of Adderall vary widely among individuals, but most commonly include insomniadry mouth, and loss of appetite. The risk of developing an addiction is insignificant when Adderall is used as prescribed at fairly low daily doses, such as those used for treating ADHD; however, the routine use of Adderall in larger daily doses poses a significant risk of addiction due to the pronounced reinforcing effects that are present at higher doses. Recreational doses of Adderall are generally much larger than prescribed therapeutic doses, and carry a far greater risk of serious adverse effects.[sources 2]

The two amphetamine enantiomers that compose Adderall (i.e., levoamphetamine and dextroamphetamine) alleviate the symptoms of ADHD and narcolepsy by increasing the activity of the neurotransmitters norepinephrine and dopamine in the brain, which results in part from their interactions with human trace amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in neurons. Dextroamphetamine is a more potent CNS stimulant than levoamphetamine, but levoamphetamine has slightly stronger cardiovascular and peripheral effects and a longer elimination half-life (i.e., it remains in the body longer) than dextroamphetamine. The levoamphetamine component of Adderall has been reported to improve the treatment response in some individuals relative to dextroamphetamine alone. Adderall’s active ingredient, amphetamine, shares many chemical and pharmacological properties with the human trace amines, particularly phenethylamine and N-methylphenethylamine, the latter of which is a positional isomer of amphetamine.[sources 3]

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Source: Wikipedia.

What are the differences between Adderall and Desoxyn?

Adderall and Desoxyn

I have an answer for you about Adderall and Desoxyn.

It’s going to be longer than it needs to be, but isn’t that just who we are?

After a year of 2 MD’s that wanted to dose me with what they felt was right and not what I felt was the best for cognitive functions with both Adderall IR’s and XR’s, then being switched to Dexedrine 5mg, after being on Adderall 60mg/day, I had all I could take and switched to my son’s MD in a larger city where new medication rules for ADHD were understood.

The first visit proved fruitful. I was offered to go back on Dexedrine at the proper conversion rate or asked if I wanted to try the Desoxyn that I had read about in forums, and found many had great success over the other choices. Not everyone liked it, but many did. Although it’s a 3 hr drive, round trip to get to the bigger city, It’s been well worth it.

Why drive a Cadillac when you can have the Mercedes.

I started on Desoxyn 10mg AM and 10mg PM and I like it. All the bullshit about it being Methamphetamine is hype intended to discourage it from being prescribed. People on here are as brainwashed as the DEA wants them to be, along with 3/4 of the Dr’s, addiction specialists and mental health workers. Sorry people, update your training and don’t lump Desoxyn in with “street meth” or people who are not ADHD.

It’s nothing like street meth at all. I’ve even pushed the envelope a bit to see what it’s like and I can’t even duplicate the effects of street meth. I’ve tried “street meth” about 10 times my whole life (I’m 56). The only “street meth” that had any effects other than making me feel like shit was “ice” once and biker meth back in the 70’s. All they did was calm me, help me focus and give me a libedo like a 14 yr old. So anyone reading this that thinks Desoxyn is like street meth, clean out your brain and get off the soap box that you don’t even know why you’re on.

Desoxyn starts out great and ends great. No big crashes, no bullshit and best of all, no side effects. A dose seems to last me a good 6-8 hours, but I’m just finishing my first month i bought from The PDR says it has about a 5 hour half life. I’m a slow metabolizer of Adderall and an IR could have me still up 16 hours later, but I’m not seeing this with the Desoxyn. Although I could still be doing what’s necessary for 12 hrs after my afternoon dose, I’m a late night person and naturally get a second wind if needed, but could also go to bed 8 hours after my last dose and not play ceiling games half the night.

Another difference I’ve seen is that with the Adderall you get what I’d call, “tunnel vision”. Only able to focus on one task at a time. Any disturbance’s for me and it ruined everything I was doing. With the Desoxyn, I can focus on several tasks at once if necessary, and any interruptions are just new challenges. “What? I’m doing 5 things at once now, and you want me to do 10? No problemo!” Yeah, no more tunnel vision. It’s great.

Adderall seemed engineered and just dirty. I was swelling up, and having cardiac issues while on it. Dexedrine, although clean, caused agitation and nervousness at the comparable dose. I understand that methamphetamine breaks down into the two amphetamines D and L, just in case someone wants to comment and say there is no differences, but I’ve not had any side effects, even when playing with the dosing, as we all do.

While Adderall would still be keeping me up, I didn’t have a choice like I do with Desoxyn, they wouldn’t stop messing with me. My daughter is also being treated for ADHD, and an Adderall IR only lasts her about 4 hrs, so she adjusts the doses to suit her best. My father along with my 3 kids are ADD including 2 out of 7 grand children, with one getting ready for her diagnosis and the others are too young to tell. Each of us process the medication differently, and I’d be considered a slow metabolizer.

With several companies making ‘’Mixed Amphetamine Salts” now, every damn pill is different. One is the quick hit, another is nervousness, another has no upfront hit but only a smoother Dexedrine effect without any real focus, while another causes severe side effects, and yet another may do nothing at all.

It’s all over the ADD forums, but most pharmacists get all professional and give you the “It’s bioequivalent” bullshit, and it’s just that, professional bullshit. My pharmacist’s son has a sleep/wake disorder and is on high amounts (90+ mg) of Adderall. One brand made him deathly sick and another does nothing for him, so he’s on one of the higher rated brands that the forums talk about.


Good luck, and I’d be interested to know if you go that way, just how you feel about them.

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